Success developing targeted therapies in oncology depends on the ability to identify new targets and develop agents that hit those targets in an efficient manner. Major clinical advances in the care of common cancers have been made through participation of patients in Phase I clinical trials of agents that achieve this goal. Predictive oncology biomarkers - i.e., genes and genetic mutations, proteins and signalling pathways implicated in the proliferation and death of cancer cells - and their use to control tumor growth has been a major advancement allowing more efficacious therapy with decreased toxicity. Our collaboration with pharmaceutical partners has been instrumental in bringing this care to our patients. Read More >